Characterization of Severe Asthma Worldwide

[Severe asthma].

Definitions of Severe Asthma

DEFINITIONS OF SEVERE ASTHMA Nomenclature is important in severe asthma. One of the first definitions of ‘difficult asthma’ was made by the European Respiratory Society (ERS) task force.5 This definition was based on the number of exacerbations, severity of symptoms, doses of ICS, add-on medication and SABA. Following this, an American Thoracic Society (ATS) workshop established the term ‘refra...

Is it severe asthma or asthma with severe comorbidities?

Severe asthma is defined as asthma that requires treatment with high-dose inhaled corticosteroids (ICSs) plus a second controller and/or systemic corticosteroids to prevent it from becoming uncontrolled or that remains uncontrolled despite this therapy. This definition has limitations: 1) it does not define any biological characteristic that distinguishes severe asthma from asthma in general an...

Severe mental illness in prisoners worldwide.

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Clinical review: Severe asthma

Severe asthma, although difficult to define, includes all cases of difficult/therapy-resistant disease of all age groups and bears the largest part of morbidity and mortality from asthma. Acute, severe asthma, status asthmaticus, is the more or less rapid but severe asthmatic exacerbation that may not respond to the usual medical treatment. The narrowing of airways causes ventilation perfusion ...